This WHO guideline focuses on enhancing the availability of health workers in rural and remote areas to achieve universal health coverage. It highlights the challenges faced by these populations, including socioeconomic inequities and limited access to essential health services. The guideline presents 17 evidence-based interventions aimed at improving the retention, recruitment, and development of a skilled health workforce. It emphasizes the need for a multi-sectoral approach involving various stakeholders to address the shortage of health workers. The guideline is intended for policymakers and aims to provide strategies for investing in rural health jobs and empowering communities, particularly youths and women.