Experts from the WHO Vector Control Advisory Group (VCAG) met with product developers, innovators and researchers from 21 to 25 October 2024 for the 21rst VCAG meeting. This report details the proceedings and outcomes of the meeting, including advice provided to applicants working on interventions in the following intervention types: systemic endectocide treatment, reduction of pathogen transmission induced by gene drive; topical repellents; spatial repellents; sterilization of male mosquitoes; bait stations; and eave tubes.