This document addresses strategies for malaria transmission control through the use of endectocide and ectocide products. It aligns with the Global Technical Strategy for Malaria 2016-2030, aiming to innovate and develop new tools to combat malaria and address insecticide resistance. The World Health Organization (WHO) identifies unmet public health needs and guides the development of relevant products through Preferred Product Characteristics (PPCs). The focus is on drugs, like ivermectin, that affect parasitic worms and mosquitoes. The document discusses the evaluation and innovation of these products to meet public health targets, emphasizing on reducing malaria transmission through effective vector control. Intended for product developers, regulatory agencies, and public health stakeholders, it provides insights into the development process of new malaria control interventions.