Repeat Amino Acid Sequences in Proteins: Biochemical and Medical Consequences
About this ebook
This volume highlights:
- Which repeat sequences have pathogenic consequences and why?
- Repeats which lead to surface hydrophobic clusters and their importance
- Role of aromatic amino acid clusters in protein‐protein and protein‐drug interactions
- Cell‐penetrating peptides and Elastin‐like peptides
- Unusual phenomenon of fluorescence observed with repeats of some non‐aromatic amino acids
- The use of residue cluster classes to represent protein structure and model structure‐function relationships.
About the author
Vladimir N. Uversky B.S., M.S., Ph.D., D.Sc., Professor at the Department of Molecular Medicine, Morsani College of Medicine, University of South Florida. He has a Ph.D. in physics and mathematics from Moscow Institute of Physics and Technology was followed by a D.Sc. in biophysics from the Institute of Experimental and Theoretical Biophysics, Russian Academy of Sciences. He is a fellow of the Royal Society of Biology, the Royal Society of Chemistry, the American Institute for Medical and Biological Engineering, and the American Association for the Advancement of Science. He has authored over 1,350 scientific publications and edited several books and book series on protein structure, function, folding and misfolding. He has an h‐index of 133. He has collaborated with more than 12,500 colleagues from more than 2,750 research organizations in 89 countries/territories.
Munishwar Nath Gupta taught chemistry, biochemistry and biotechnology at IIT Delhi [1975‐2018]. He has a Ph.D. in biochemistry from IISc Bangalore was followed by post‐docs at the University of Minnesota, USA; MIT, USA; UTC, France and Lund University, Sweden. He is a fellow of NASI, Allahabad and INSA, New Delhi. He is currently Series Editor of Foundations and Frontiers in Enzymology, Elsevier. He has published over 300 scientific articles and edited 7 books so far. His current h‐index is 64.
