Transmissible Spongiform Encephalopathies:: Scrapie, BSE and Related Human Disorders
Bruce W. Chesebro
нояб. 2013 г. · Current Topics in Microbiology and Immunology Книга 172 · Springer Science & Business Media
Электронная книга
288
Количество страниц
reportОценки и отзывы не проверены. Подробнее…
Об электронной книге
In spite of a long history of intense investigation the transmissible spongiform encephalopathies remain a poorly understood family of neurodegenerative diseases. This group of diseases has been described in a wide variety of animal species and includes kuru, Creutzfeldt-Jakob disease, and Gerstmann-Straussler syndrome in humans, and scrapie, bovine spongiform encephalopathy, and related syndromes in ruminants and rodents. In all cases spongiform degeneration and astrocytosis are seen in specimens of brain and a filterable transmissible agent is present in the brain and some other tissues of affected individuals. However, the precise nature of this agent remains unknown. Agent infectivity, which can so far only be assayed by serial transmission to new individuals, be remarkably resistant to inactivation has been shown to by heat, chemicals, and irradiation. These properties create significant biohazard possibilities during exposure to infected tissues. Transmission between humans was originally reco gnized in the unique epidemiology of kuru in New Guinea tribesmen, and concern about transmission from animals to humans has re-emerged as a result of the current epidemic of bovine spongiform encephalopathy in dairy cattle in Great Britain. Although interspecies transmission has often been achieved experimentally, its efficiency is highly variable. There fore, the possibility of spread of bovine spongiform encephalopathy from cattle to humans or various animal populations cannot be accurately predicted at this time. This volume presents a comprehensive update of know ledge concerning the transmissible spongiform encephalo pathies.
Оцените электронную книгу
Поделитесь с нами своим мнением.
Где читать книги
Смартфоны и планшеты
Установите приложение Google Play Книги для Android или iPad/iPhone. Оно синхронизируется с вашим аккаунтом автоматически, и вы сможете читать любимые книги онлайн и офлайн где угодно.
Ноутбуки и настольные компьютеры
Слушайте аудиокниги из Google Play в веб-браузере на компьютере.
Устройства для чтения книг
Чтобы открыть книгу на таком устройстве для чтения, как Kobo, скачайте файл и добавьте его на устройство. Подробные инструкции можно найти в Справочном центре.
