Tissue Remodeling and Epithelial Morphogenesis

ยท Current Topics in Developmental Biology ืกืคืจ 89 ยท Elsevier
ืกืคืจ ื“ื™ื’ื™ื˜ืœื™
240
ื“ืคื™ื
ื›ืฉื™ืจ
ื”ื‘ื™ืงื•ืจื•ืช ื•ื”ื“ื™ืจื•ื’ื™ื ืœื ืžืื•ืžืชื™ืย ืžื™ื“ืข ื ื•ืกืฃ

ืžื™ื“ืข ืขืœ ื”ืกืคืจ ื”ื“ื™ื’ื™ื˜ืœื™ ื”ื–ื”

For more than 30 years, Current Topics in Developmental Biology has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelials, this thematic volume represents a timely and valuable contribution to an exciting and multidisciplinary field of study. Because defects in epithelial function and growth control play a major role in human diseaseโ€”cancerous tumors, spina bifida, cardiac malformations, for exampleโ€”this volume will be of particular interest to researchers working in cancer drug design and development and those working in therapeutic areas to treat developmental abnormalities. - Coverage of current research findings and thought on cell-cell and cell-extracellular matrix interactions gives researchers a better understanding of the processes of remodeling and morphogenesis, which are critical to the development of drugs aimed at disrupting the early formation and proliferation of cancerous tumors - Inclusion of chapters that discuss the most contemporary thought on cell polarity and tissue morphogenesis, providing researchers with a better understanding of the control of cellular organization and polarity (particularly important to researchers who are developing treatments for developmental abnormalities and those working in cancer drug development) - Use of a variety of animal models, allowing researchers to compare and contrast the molecular mechanisms that underlie cell-cell and cell-extracelluar matrix interactions in a variety of research models

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