Targeted Protein Degradation

George M. Burslem is currently an Assistant Professor for Biochemistry and Biophysics at the Perelman School of MedicineDepartment of Biochemistry and Biophysics and Department of Cancer Biology, University of Pennsylvania. He was previously a Postdoctoral Fellow at Yale University. He completed his PhD. in the University of Leeds, and his MSci in the University of BristolProf. Burslem's lab is interested in developing chemical tools to understand and modulate lysine post-translational modifications, specifically acetylation and ubiquitination. His laboratory is particularly interested in novel pharmacological approaches to modulate post-translational modifications which regulate gene expression and protein stability, employing a multidisciplinary approach including synthetic chemistry, biochemistry, biophysics and cell biology to probe biological systems in cancer biology.