Targeted Protein Degradation

· Methods in Enzymology Libro 681 · Elsevier
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Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, with each. Each written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Methods in Enzymology serials - Updated release includes the latest information on Targeted Protein Degradation

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George M. Burslem is currently an Assistant Professor for Biochemistry and Biophysics at the Perelman School of MedicineDepartment of Biochemistry and Biophysics and Department of Cancer Biology, University of Pennsylvania. He was previously a Postdoctoral Fellow at Yale University. He completed his PhD. in the University of Leeds, and his MSci in the University of BristolProf. Burslem's lab is interested in developing chemical tools to understand and modulate lysine post-translational modifications, specifically acetylation and ubiquitination. His laboratory is particularly interested in novel pharmacological approaches to modulate post-translational modifications which regulate gene expression and protein stability, employing a multidisciplinary approach including synthetic chemistry, biochemistry, biophysics and cell biology to probe biological systems in cancer biology.

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