Signaling Pathways in Liver Diseases
C. Trautwein · Jean-Francois Dufour · R. Graf · Pierre-Alain Clavien
Aug. 2005 · Springer Science & Business Media
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Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.
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Prof. J.-F. Dufour, hepatologist at the University of Bern, is internationally recognized for bridging basic science and clincial practice.
Prof. P.-A. Clavien, head of visceral surgery University Hospital Zürich, is a world renown investigator in the field of liver ischemia/reperfusion injury.
Prof. Clavien successfully lead multi-authored texts having already published 3 books as editor:
Malignant Liver Tumors, Blackwell Science Inc., May 1999
Medical Care of the Liver Transplant Patient (Killenberg/Clavien), Blackwell Science Inc.
Diseases of the Gallbladder and Bile Ducts: Diagnosis and Treatment (Clavien/Baillie),Blackwell Science Inc.
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