The TNM System is the most widely used classification of the extent of localgrowth and regional and distant spread of cancer. The 1992 revision of the fourth edition agreed upon by all national TNM committees, includes: changesmade by FIGO in 1989/1990; an updated classification of urological tumours; and new classifications of small intestine carcinomaand pleural mesothelioma. In addition, ICD-O codes have been updated according to the 1990 second edition.