Intracellular Delivery: Harnessing DNA Structures for Targeted Cellular Precision

Chapters Brief Overview:

1: Intracellular delivery: Introduction to the delivery of substances into cells and its relevance in DNA origami.

2: Cellpenetrating peptide: Exploration of peptides designed to facilitate cellular entry for DNA delivery.

3: Tissue nanotransfection: Examines the use of nanotechnology in transferring genetic material into tissues.

4: Small interfering RNA: Discusses the role of siRNA in gene silencing and its applications in gene therapy.

5: Cationic liposome: Details the use of liposomes in gene delivery, focusing on their structure and functionality.

6: Genetic engineering techniques: Overview of genetic modifications used to enhance DNA delivery and therapeutic outcomes.

7: Magnetassisted transfection: Describes how magnetic fields aid in transfecting cells with genetic material.

8: Gene delivery: A broad look at methods and advancements in delivering genes into cells for therapeutic purposes.

9: Transfection: Provides a comprehensive study of various transfection techniques, a key element of genetic engineering.

10: Nanoinjection: Focuses on the precise delivery of DNA using nanotechnological methods, including its applications.

11: Electroporation: Discusses the electrical techniques used to introduce DNA into cells and their relevance.

12: DNA construct: Explores the design and construction of DNA molecules for therapeutic purposes.

13: Exogenous DNA: Details the incorporation of foreign DNA into cells and its significance in gene therapy.

14: MRNA vaccine: Examines the use of mRNA vaccines in combating diseases and their groundbreaking implications.

15: Genetic vaccine: Covers genetic vaccines' mechanisms and their potential in preventing various diseases.

16: Lentivirus: An indepth look at lentiviruses as vectors for gene delivery in research and therapy.

17: Sonoporation: Discusses the use of ultrasound in enhancing gene delivery, focusing on sonoporation techniques.

18: Hydrodynamic delivery: Describes methods of DNA delivery through hydrodynamic pressure, especially for large molecules.

19: Vectors in gene therapy: An exploration of various viral and nonviral vectors used in modern gene therapies.

20: Magnetofection: Analyzes the role of magnetic nanoparticles in improving the efficiency of gene delivery.

21: RNA therapeutics: Investigates the emerging field of RNAbased therapies and their potential to revolutionize medicine.

"Intracellular Delivery" not only explains the science behind each technique but also ties them together, presenting a unified picture of the advances in gene therapy and molecular medicine. This book is an essential reference for anyone in the field of DNA origami or molecular biology.