Rational Basis for Clinical Translation in Stroke Therapy

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· CRC Press
Ebook
538
Pages
Eligible
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About this ebook

Stroke remains one of the major causes of death and long-term disability worldwide. Currently, the only approved therapy for the acute treatment of this disease is thrombolysis, a strategy that can only be applied to a small percentage of patients due to its narrow therapeutic window. Unfortunately, during the last years numerous promising drugs th

About the author

Giuseppe Micieli is director of the Department of Emergency Neurology at the IRCCS "C. Mondino" Foundation in Pavia, Italy, as well as adjunct professor at the University of Pavia. He received his degree in medicine and surgery from the University of Pavia and holds specialization degrees in neurology and clinical pharmacology. He is former director of the Laboratory of Vegetative Physiopathology, the Headache Centre, and the Sub-intensive Unit of Cerebrovascular Diseases at the IRCCS "C. Mondino" Foundation. He is also the former leader of the Emergency Neurology and Stroke Unit of the Humanitas Clinical Institute in Rozzano, Milan. Dr. Micieli has published more than 170 peer-reviewed articles and held numerous leadership positions including coordinating roles for the Stroke Unit Network and the Italian Stroke Forum.

Diana Amantea is aggregate professor of pharmacology in the Department of Pharmacy, Health Sciences and Nutrition at the University of Calabria, Italy. She also leads the Stroke Research Unit at the Center of Preclinical and Translational Pharmacology located in the University of Calabria. Dr. Amantea received her PharmD from the University of Calabria and her PhD in pharmacology from the University of Birmingham. Her research focuses on understanding the inflammatory mechanisms occurring during ischemic brain injury in order to identify novel pharmacological targets for stroke therapy.

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