Nucleic Acid Design: Engineering DNA for Molecular Innovation and Synthetic Biology

Chapters Brief Overview:

1: Nucleic acid design – Learn how tailored sequences drive structural formation and nanotechnological functions.

2: Denaturation (biochemistry) – Explore the thermal and chemical factors influencing nucleic acid stability.

3: Nucleic acid structure prediction – Discover computational tools predicting secondary and tertiary formations.

4: Triplestranded DNA – Understand the mechanics and applications of threestranded nucleic acid structures.

5: Base pair – Examine the fundamental interactions forming the genetic code and structural frameworks.

6: DNA nanotechnology – Investigate how DNA is manipulated to create selfassembling nanostructures.

7: Helicase – Study the molecular motors unwinding DNA for replication and repair processes.

8: ViennaRNA Package – Utilize computational software for RNA secondary structure predictions and analysis.

9: Nucleic acid tertiary structure – Analyze the higherorder folding principles essential for function.

10: Nucleic acid thermodynamics – Understand the energetic principles governing nucleic acid stability.

11: RNA origami – Explore the art of folding RNA into intricate, functional nanostructures.

12: Spherical nucleic acid – Investigate nanoscale spherical architectures with biomedical applications.

13: Holliday junction – Delve into the structural dynamics of recombination intermediates.

14: Hoogsteen base pair – Examine alternative hydrogen bonding patterns and their biological significance.

15: Nucleic acid secondary structure – Learn how sequence dictates hairpins, loops, and other formations.

16: Nucleic acid double helix – Revisit the canonical structure that underpins genetic information.

17: Nucleic acid structure – Analyze the interplay of primary, secondary, and tertiary formations.

18: Peptide nucleic acid – Discover synthetic nucleic acid analogs with unique stability and binding properties.

19: Noncanonical base pairing – Investigate unconventional interactions that expand structural complexity.

20: DNA origami – Learn how DNA strands are folded into programmable nanostructures.

21: TectoRNA – Examine modular RNA structures enabling complex selfassembly and function.

Mastering nucleic acid design opens doors to innovations in medicine, nanotechnology, and synthetic biology. This book provides a structured, indepth guide tailored to learners and experts alike, offering knowledge that far outweighs its cost. Expand your expertise and explore the limitless potential of DNA nanotechnology today.