We recall and improve our 2019 and 2020 concepts of n-SuperHyperGraph, Plithogenic nSuperHyperGraph, n-Power Set of a Set, and we present some application from the real world. The nSuperHyperGraph is the most general form of graph today and it is able to describe the complex reality we live in, by using n-SuperVertices (groups of groups of groups etc.) and nSuperHyperEdges (edges connecting groups of groups of groups etc.).