Development of Neural Circuitry

Oliver Hobert

2009年5月 · Current Topics in Developmental Biology 87 巻 · Academic Press

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The nervous system is highly complex both in its structural order and in its ability to perform the many functions required for survival and interaction with the environment; understanding how it develops has proven to be one of the greatest challenges in biology. Such precision demands that key events at every developmental stage are executed properly and are coordinated to produce the circuitry underlying each of the adult nervous system's functions. This volume describes the latest research on the cellular and molecular mechanisms of neural circuitry development, while providing researchers with a one-stop overview and synthesis of contemporary thought in the area. - Reviews current research findings on the development of neural circuitry, providing researchers with an overview and synthesis of the latest contemporary thought in the cellular and molecular mechanisms that underlie the development of neural circuitry - Includes chapters discussing topics such as the guidance of nerve growth and the formation of plasticity of synapses, helping researchers better understand underlying mechanisms of neural circuit development and maintenance that may play a role in such human diseases/conditions as depression, anxiety, and pain - Chapters make use of a variety of human and animal models, allowing researchers to compare and contrast neural circuitry development across a wide spectrum of models