Experimental Models of Infection, Inflammation and Injury
David Montrose
Mar 2022 · Methods in Cell Biology Book 168 · Academic Press
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About this ebook
Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems. Chapters in this new release include Induction and Evaluation of Murine T Cell Transfer Colitis, Modelling acute graft-versus-host disease (aGVHD) in murine bone marrow transplantation (BMT) models with MHC disparity, Mouse models of Graft-Versus-Host Disease, Preclinical Model of Multiple Sclerosis: Methods in Autoimmune Demyelination, Preclinical model of Multiple Sclerosis: focal, chemical or demyelination, Investigating demyelination, efficient remyelination and remyelination failure in organotypic cerebellar slice cultures: workflow and practical tips, and more. Other notable sections cover Rheumatoid Arthritis: Methods for Two Murine Models, Induction of Pancreatitis in Mice with Susceptibility to Pancreatic Cancer, Small Animal Models of Thermal Injury, Large Animal Models of Thermal Injury, Small animal models of localized heart irradiation, Methods for Induction and Assessment of Intestinal Permeability in Rodent Models of Radiation Injury, and more. - Provides precise, step-by-step guidance on how to implement experimental systems - Presents a comprehensive background on the disease the model is being used to study - Offers insights into how the described disease models compare to other existing systems
About the author
Dr. Montrose received his B.A. in Biology from Manhattanville College and his Ph.D. in Biomedical Science from the University of Connecticut (Health Center campus). He received his post-doctoral training at Weill Cornell Medical College of Cornell University. He is currently an Assistant Professor and lab head in the Department of Pathology at Stony Brook University School of Medicine and a member of the Stony Brook Cancer Center. Dr. Montrose is also a member of the Molecular and Cellular Pharmacology (MCP) and Molecular Genetics and Microbiology (MGM) graduate programs.
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