Biointegration of Medical Implant Materials: Science and Design

Chandra P. Sharma

Jul 2010 · Elsevier

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Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. - Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration - Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction - Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery

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Dr. Chandra P. Sharma is a former Adjunct Professor, Department of Pharmaceutical Biotechnology, Manipal College of Pharmaceutical Sciences, Manipal University, and Hon. Emeritus Professor, College of Biomedical Engineering and Applied Sciences, Purbanchal University, Kathmandu, Nepal. Dr. Sharma is a Solid-State Physicist from IIT Delhi and received his training in biomaterials area in the University of Utah with Prof. D.J. Lyman as a graduate student and in the University of Liverpool, England, with Prof. D.F. Williams as a Post-Doctoral Research Associate. Dr. Sharma has been awarded FBSE (Fellow Biomaterials Science and Engineering) by the International Union of Societies for Biomaterials Science and Engineering (IUS-BSE) in 2008 and FBAO (Fellow Biomaterials and Artificial Organs) by the Society for Biomaterials and Artificial Organs (India) (SBAOI) in 2011 and [17020_LE1] shares Whitaker and National Science Foundation Award—International Society for Artificial Organs (ISAO) USA, invited member ACS (2015–2018). [17020_LE1]Please check the phrase “and shares Whitaker and National... for clarity and amend if necessary.

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