Bioinformatics and Functional Genomics

· John Wiley & Sons
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"Introduction to Bioinformatics" ist eine breit angelegte Einführung in die Bioinformatik.

Der Band gliedert sich in drei Abschnitte zu biologischen Sequenzdaten, kompletten Genomen und bioinformatischen Ansätzen zur Problemlösung bei der Sequenzanalyse, Microarrays und Krankheiten des Menschen.

Erfahrung im Umgang mit rechnergestützten Methoden wird nicht vorausgesetzt.

"Introduction to Bioinformatics" kombiniert Theorie und praktische Anwendung in einem ausgewogenen Verhältnis.

Jedes Kapitel enthält Problemstellungen, Computeraufgaben, Software Pakete, Web Links und einen praktischen "How To"-Abschnitt, der genau erklärt, wie man frei zugängliche Software nutzen kann.

Der Band erläutert darüber hinaus auch die Schwachstellen der verschiedenen Ansätze.

Mit drei ausführlichen Beispielen.

Mit einem Glossar.

Mit einem Lösungsteil zu den Problemstellungen.

Mit einer Bibliographie weiterführender Literatur.

Acerca do autor

Jonathan Pevsner received his Ph.D. in Pharmacology and Molecular Sciences at the Johns Hopkins School of Medicine (1989). There, he identified an odorant-binding protein in nasal secretions. He completed postdoctoral training as a Helen Hay Whitney fellow in the Department of Molecular Physiology at the Stanford University Medical Center. At Stanford he identified proteins that function in neurotransmitter release at nerve terminals. In 1995 he joined the faculty in the Department of Neurology at the Kennedy Krieger Institute and the Department of Neuroscience at the Johns Hopkins School of Medicine. He began teaching bioinformatics in 1996, and introduced a ten-week course in 2000. In 2001 the graduate students voted him Teacher of the Year, and in 2003 the Johns Hopkins faculty gave him the Professor’s Award for Excellence in Teaching. His lab studies the molecular basis of childhood neurological disorders including autism and Down Syndrome, and develops bioinformatics software.

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