Computational Approaches to Natural Products Discovery

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· Methods in Enzymology Book 720 · Academic Press
Ebook
412
Pages
Eligible
This book will become available on October 15, 2025. You will not be charged until it is released.

About this ebook

Computational Approaches to Natural Products Discovery provides descriptions of the latest techniques in computational methods for the study of natural products. The techniques covered are related to genome mining, natural product biosynthesis, natural product evolution, and natural product structure. Readers will learn how to use these techniques to advance their own work in natural product discovery. - Provides descriptions of computational methods for natural product discovery by experts in the field - Discusses challenges in natural product discovery - Includes methods that address multiple steps in the natural product discovery pipeline

About the author

After completing studies for the A.B., A.M., and Ph.D. degrees in chemistry at Harvard University, David W. Christianson joined the faculty of the University of Pennsylvania, where he is currently the Roy and Diana Vagelos Professor in Chemistry and Chemical Biology. At Penn, Christianson’s research focuses on the structural and chemical biology of the zinc-dependent histone deacetylases as well as enzymes of terpene biosynthesis. His research accomplishments have been recognized by several awards, including the Pfizer Award in Enzyme Chemistry and the Repligen Award in Chemistry of Biological Processes from the American Chemical Society, a Guggenheim Fellowship, and the Elizabeth S. and Richard M. Cashin Fellowship from the Radcliffe Institute for Advanced Study at Harvard University. Christianson is also a dedicated classroom teacher, and his accomplishments in this regard have been recognized by the Lindback Award for Distinguished Teaching at Penn and a Rhodes Trust Inspirational Educator Award from Oxford University. Christianson has also held visiting professorships in the Department of Biochemistry at Cambridge University and the Department of Chemistry and Chemical Biology at Harvard University. Christianson has served with Prof. Anna Pyle as Co-Editor-in-Chief of Methods in Enzymology since 2015.

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