Nanomedicine stands out as a paradigm shift in healthcare, offering unprecedented possibilities for diagnosing, treating, and preventing diseases. The interdisciplinary nature of nanomedicine is a cornerstone of its innovative potential, bringing together experts from physics, chemistry, biology, and engineering to tackle some of the most pressing challenges in medicine. Nanomedicine combines nanoparticles’ unique properties—such as their small size, high surface-to-volume ratio, tunable surface chemistry, magnetic capabilities, and optical properties—with the latest biomedical research to create innovative tools for modern healthcare. The unique properties of nanoparticles make them invaluable in biomedical applications, from targeted drug delivery systems to diagnostic imaging. Understanding how nanoparticles interact with cells, including their entry mechanisms and the biological responses they elicit, is crucial for optimizing their use in therapeutic applications. This primer is an introduction to the field, outlining the fundamental principles, current applications, and future directions of nanomedicine.

As the field evolves, interdisciplinary cooperation will be key to advancing nanomedicine and unlocking its full potential. The authors hope this primer provides readers with a clear understanding of the principles governing nanomedicine and inspires further exploration into this dynamic and rapidly growing area of research. By bridging the gap between scientific discovery and clinical application, nanomedicine can shape the future of healthcare and redefine therapeutic possibilities.